Bone Marrow Transplant at CritiCare Asia Hospitals, Kurla
A bone marrow or stem cell transplant is considered when the body's blood-forming cells have stopped working properly, whether because of cancer, an inherited condition, or another blood disorder. CritiCare Asia Hospitals is a bone marrow transplant hospital in Mumbai where patients and families receive a clear explanation of what this treatment involves, including its risks. It is a demanding treatment and has to be matched carefully to what each patient's condition needs. At the Kurla centre, evaluation for bone marrow transplant in Kurla, Mumbai begins with a structured assessment before any recommendation is made.
Symptoms That Point to a Blood or Marrow Disorder
Problems in the marrow often show through the blood. Signs that call for medical review include:
- Tiredness and weakness that do not lift with rest
- Frequent or lingering infections
- Easy bruising, nosebleeds or bleeding gums
- Pale skin and breathlessness on mild effort
- Bone pain or swollen glands
- Fever with no clear cause
- Unplanned weight loss
These signs do not mean a transplant is needed. They indicate that blood tests and a bone marrow transplant specialist opinion are due.
What Bone Marrow and Stem Cells Do
Bone marrow is the soft tissue inside bones where blood cells are made. It holds stem cells, which develop into red cells, white cells and platelets. These carry oxygen, fight infection and help blood to clot. When this process breaks down, because of disease, chemotherapy or a genetic disorder, the body can no longer make healthy blood cells by itself.
When a Transplant Is Considered
A haematopoietic stem cell transplant is used in children and adults, and the diagnosis shapes almost every decision that follows.
- Blood cancers such as leukaemia and lymphoma, where diseased marrow is replaced with healthy stem cells
- Aplastic anaemia, where the marrow stops producing enough blood cells
- Inherited blood disorders, including thalassaemia and certain bleeding disorders present from birth
- Immune deficiency syndromes that stop the immune system from working properly
- Certain metabolic disorders caused by an enzyme or biochemical defect
Types of Transplant
The type depends on where the stem cells come from and on the patient's condition.
- Autologous transplant
the patient's own stem cells, collected and stored before high-dose treatment, then given back - Allogeneic transplant
cells from a matched donor, usually a sibling or other compatible relative, or an unrelated donor when no family match exists - Peripheral blood stem cell transplant
cells collected from the bloodstream and not directly from the marrow - Umbilical cord blood transplant
cells from cord blood, considered when no matched donor is otherwise available
Stem cells can be taken from the marrow through a minor surgical procedure, from circulating blood after a mobilising medicine, or from cord blood donated at birth. The transplant team advises which source suits the donor situation and the patient's condition.
Eligibility and Donor Identification
Eligibility is assessed through blood tests, imaging and organ function tests, to confirm the patient can tolerate conditioning treatment and the transplant itself. For an allogeneic transplant, tissue typing (HLA matching) identifies a compatible donor, starting with siblings and close relatives before moving to unrelated donor registries or cord blood. The closer the match, the lower the risk of complications, so donor identification is a careful, staged process.
Before, During and After the Transplant
Before: Detailed tests confirm the diagnosis and fitness for transplant, along with donor matching where needed. Conditioning treatment, usually chemotherapy and sometimes radiation, prepares the body to receive new stem cells.
During: The stem cells are given by infusion, much like a blood transfusion, and not through surgery. They travel to the bone marrow and begin making new blood cells over the following weeks.
After: The period just after transplant is closely monitored, because the immune system remains very weak until new cells establish themselves. Patients are cared for in a controlled environment that reduces infection risk, with regular blood counts to confirm that the new marrow is working. Recovery continues well past discharge, with structured follow-up to watch for complications and confirm the transplant has taken hold.
Bone Marrow Transplant at CritiCare Asia Hospitals, Kurla
Bone marrow transplant carries real risks alongside its benefits, so care at Kurla is built around careful patient selection, coordinated input from haematology and transplant specialists, and infection-control measures designed for this vulnerable recovery period. Families are involved throughout, and the expected costs are explained in plain terms.
If a blood disorder, immune condition or cancer diagnosis has raised the possibility of a transplant, book a consultation with the transplant team at CritiCare Asia Hospitals, Kurla, and ask for the evaluation plan and estimate in writing.